If you´d like to drop-off your vehicle in another city or state, you must first check with the rental company to see if there are any restrictions in doing so. It is possible to drop-off your vehicle in a location other than the one from where you picked it up so long as the rental company authorizes it.
Note, though, that dropping off your vehicle in a different location will most likely incur a one-way fee. This fee is calculated proportionately to the distance between pick-up and drop-off locations and will also account for the rental company’s administrative expenses. Make sure you´re aware of the cost before signing your rental agreement.